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Title: Blog by Novelist William S. Frankl, MD

Archive for August, 2018

LouisPasteur/19th Century Microbiologist

Thursday, August 2nd, 2018

Louis Pasteur successfully tested his rabies vaccine on July 6 in 1885. Pasteur had begun work on a vaccine in 1882, using a weakened form of the virus taken from the spinal cords of infected animals. The research was time-consuming, because it took several weeks for the virus to reach his test animals’ brains after they were infected, but Pasteur soon realized that people didn’t need to have the vaccine on board before they were bitten, as with other diseases. The delay between the rabid animal’s bite and the outbreak of the disease meant the vaccine could be given only when needed, and it would have plenty of time to work.

In 1885, a nine-year-old boy named Joseph Meister was bitten by a rabid dog. He was brought to Pasteur, and though Pasteur didn’t feel his vaccine was sufficiently tested yet, he knew the boy would certainly die otherwise, so he took a chance. It was a tense few weeks waiting to see if Meister would come down with the disease, but the boy recovered, and three months later was pronounced in good health. Pasteur’s fame spread quickly, and the era of preventative medicine had begun.

Franz Kafka/ Great Czech Author

Thursday, August 2nd, 2018

July 3 was the birthday of writer Franz Kafka (1883) , who wrote the story The Metamorphosis, about a traveling salesman named Gregor Samsa who wakes up one day transformed into a hideous insect. Many consider it the finest short story ever written. All of Kafka’s most famous works were published after his death, and all contain surrealistic elements that led to the phrase “Kafkaesque,” as a descriptor for bizarre, dark stories.

He was born into a middle-class Jewish family in Prague, the oldest of six children. His father was a temperamental, controlling man, and two of Kafka’s brothers died in infancy. Later, three of his sisters died in concentration camps during the Holocaust. Kafka was a fine student and went on to train as a lawyer, though his heart wasn’t in it, and he later found better work at an insurance company, which allowed him plenty of time to work on his stories.

Kafka was always anxious, and frequently suffered from depression and illnesses. Some historians now believe he may even have suffered from anorexia nervosa and schizophrenia, which may explain some of the more surrealistic plots in his work. In his diary, he once wrote: “The tremendous world I have in my head! But how to free myself, and free it, without being torn in half. And a thousand times sooner be torn in half than keep it in me or bury it. For this I’m here, that’s quite clear to me.”

One of Franz Kafka’s most famous works is The Trial (1925), about a man arrested and prosecuted by remote authorities. The man, and the reader, never learn exactly what the man’s crimes were. He wrote The Judgment (1913) in a frenzy over one night in September 1922. He called that story “a complete opening of body and soul.” During his lifetime, he burned more than 90 percent of his work. He hated most of The Metamorphosis, saying, “Unreadable ending. Imperfect almost to its very marrow.”

Franz Kafka died from tuberculosis at the age of 40 in 1924.

Before he died, he wrote a request to his friend Max Brod: “Dearest Max, my last request: Everything I leave behind me … in the way of diaries, manuscripts, letters (my own and others), sketches and so on, to be burned unread.”

Max Brod ignored his wishes and after Kafka died, made sure that his works were published, and Kafka became famous. In 1988, a handwritten manuscript of The Trial sold at auction for $1.98 million.

 


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